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Nakamoto N, Kanai T (2014) Role of toll-like receptors in immune activation and tolerance in the liver

A significant limitation of current studies on lactylation is their predominant reliance on mouse models that represent only specific pathological features, which do not fully reflect the actual conditions of patients brains

Preclinical and limited human studies indicate DSIP may modulate the hypothalamicpituitaryadrenal (HPA) axis and support healthy cortisol rhythms, making it of interest in stress-related sleep disruption

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